Albumin is the most abundant protein present in plasma, so much so that alone it accounts for about two-thirds of the total protein content. This protein is synthesized by the liver and its main functions are: transporting metabolites (such as bilirubin, free fatty acids, thyroid hormones), maintaining oncotic pressure (essential for the distribution of fluids in the capillaries and tissues) and being used as a reserve of amino acids.
Generally, albumin is secreted through the urine only in small amounts. When the values of this protein in the urine exceed the reference levels it has to do with pathological albuminuria, that can be caused by: hypertension, diabetes, kidney disease, amyloidosis and systemic lupus erythematosus. Other factors that can affect urine albumin values are: smoking, dehydration, excessive exercise, urinary tract infections, heart failure, hypertriglyceridemia and obesity.
WHO IS THIS TEST FOR?
KIDNEYS ALBUMIN TEST is aimed at anyone who wants to verify the presence of albumin in the urine outside the norm.
The presence of this protein in the urine can be an early indicator of possible kidney damage. People who chronically have small measurable amounts of albumin in their urine are at increased risk of developing progressive renal dysfunction and cardiovascular disease.
KIDNEYS ALBUMIN TEST is a rapid immunochromatographic device capable of detecting the presence of albumin in urine equal to or greater than the cut-off of 10 μg/mL.
1 test cassette
1 pipette for urine sampling
instructions for use
Open the foil bag, take out only the test cassette and throw away the desiccant bag;
Collect the urine sample in a clean, dry and residue-free container (not supplied with the kit);
Press the bulb of the pipette and immerse the tip of the pipette in the collected sample, then release the bulb;
Deposit 3 drops of the extracted sample and wait 5 minutes before reading the result.
Negative: urine albumin levels are normal or in any case below the cut-off value of 10 μg/mL.
Positive: the levels of albumin in the urine are above normal and it is therefore recommended to consult a doctor.
1. Urinary biomarkers of kidney dysfunction. Ann Biol Clin (Paris). 2015 Mar-Apr;73(2):151-7. doi: 10.1684/
2. Lopez-Giacoman, Salvador and Magdalena Madero. “Biomarkers in chronic kidney disease, from kidney
function to kidney damage” World journal of nephrology vol. 4,1 (2015): 57-73.
3. Sacks, David B et al. “Guidelines and recommendations for laboratory analysis in the diagnosis and
management of diabetes mellitus” Diabetes care vol. 34,6 (2011): e61-99
The test has been carried out correctly when the instructions for use are followed, including the reading time and interpretation of the results shown at the "RESULTS INTERPRETATION" section of the instructions for use.
It is advisable to carry out the test with the first urine of the morning, in the presence of symptoms affecting the urinary tract or in case of suspected hyperglycaemia and hypertriglyceridemia. The test can also be use during pregnancy.
The color and intensity of the lines do not affect the interpretation of the result. The lines must be smooth and full. The test has to be considered negative regardless of the color intensity of the test line (T).
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